Pymerase

A tool intended to generate a python object model, relational database, and an object-relational model connecting the two using UML or XML. However, it has been extended to also output GUI widgets and can be easily extended to output whatever else you might like. [Open source, MIT License]
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PyCrust - The Flakiest Python Shell

An interactive, graphical Python shell written in Python using wxPython.
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bridgekeeper

A Perl to Python source code converter.
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Wing IDE

A powerful development environment for the Python programming language. [Commercial]
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ActiveState - Python tools and resources

Python Solutions -professional tools to meet the needs of all Python users
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Hap Python Remote Debugger

A remote debugger and IDE that can also be used for local debugging.
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Psyco

Specializing (like a dynamic) compiler for Python, runs code 2-100 times faster, needs much memory; makes high level language faster. Descriptions, downloads (program, website), documents, news, links. [Open Source, MIT]
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ePolyglot

An Eiffel library for using the languages Eiffel, Python and Haskell together. [Open Source, zlib/libpng license]
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Visual Python

A Python development environment plug-in for Visual Studio .NET. [Commercial]
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decompyle

Converts Python byte-code back into equivalent Python source. It accepts byte-code from any Python version starting with 1.5.
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Pyrex

A Python-like language for writing extension modules.
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readline.py

Alternative Readline implementation for Python under Win32.
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F2PY

A Fortran to Python Interface Generator. [Open Source, LGPL]
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PyReverse

A set of tools for reverse engineering Python code, including creation of files readable by ArgoUML. [Open Source, GPL]
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Tixapps Applications Framework

Tixapps applications are a suite of development applications that run with  Tk/Tcl or Python, using the Tix widget set. [Open Source, BSD-like]
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